Recent Projects

ENDOCRINE PROGRAMS

  • Peptide covalently bound to MAb for diabetes indication (Biologic)
  • DPP4 inhibitor for diabetes indication (Small Molecule)
  • Cell therapy/implantable device for treatment of diabetes (Combination Biologic/Device)

DERMATOLOGY PROGRAMS

  • Small molecule treatment for psoriasis (Small Molecule)

CARDIOVASCULAR PROGRAM

  • Gene-based therapeutic for peripheral limb ischemia (Biologic)
  • Gene-based therapeutic for coronary artery disease (Biologic)
  • Recombinant protein for treatment of heart disease (Biologic)

HEMATOLOGY PROGRAM

  • Gene-based therapeutic for clotting Factor IX deficiency (Biologic)

ONCOLOGY PROGRAMS

  • Peptide covalently bound to MAb (Biologic)
  • Genetically modified autologous dendritic cells with small molecule activator for treatment of prostate cancer. (Combination Biologic/Drug)
  • Transgenic lymphocyte immunization for treatment of solid tumors. (Biologic)
  • Genetically modified donor lymphocyte infusion with small molecule activator for treatment of Graft-vs-Host Disease in hematologic malignancy (Combination Biologic/Drug)

INFECTIOUS DISEASE VACCINE PROGRAMS

  • Master File for production of adenoviral vector (Biologic)
  • Vaccines based on genetically modified parasite, and on antigen expressing plasmid vectors