Recent Projects

ENDOCRINE PROGRAMS

• Peptide covalently bound to MAb for diabetes indication (Biologic)

• DPP4 inhibitor for diabetes indication (Small Molecule)

• Cell therapy/implantable device for treatment of diabetes (Combination Biologic/Device)

DERMATOLOGY PROGRAMS

• Small molecule treatment for psoriasis (Small Molecule)

CARDIOVASCULAR PROGRAM

• Gene-based therapeutic for peripheral limb ischemia (Biologic)

• Gene-based therapeutic for coronary artery disease (Biologic)

• Recombinant protein for treatment of heart disease (Biologic)

HEMATOLOGY PROGRAM

• Gene-based therapeutic for clotting Factor IX deficiency (Biologic)

ONCOLOGY PROGRAMS

• Peptide covalently bound to MAb (Biologic)

• Genetically modified autologous dendritic cells with small molecule activator for treatment of prostate cancer. (Combination Biologic/Drug)

• Transgenic lymphocyte immunization for treatment of solid tumors. (Biologic)

• Genetically modified donor lymphocyte infusion with small molecule activator for treatment of Graft-vs-Host Disease in hematologic malignancy (Combination Biologic/Drug)

INFECTIOUS DISEASE VACCINE PROGRAMS

• Master File for production of adenoviral vector (Biologic)

• Vaccines based on genetically modified parasite, and on antigen expressing plasmid vectors